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Testing systems, controls, reagents, and other products for used to calibrate clinical drug tests, identify drugs of abuse in patient samples, and monitor patients receiving drug therapy.
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The Meso Scale Discovery V-PLEX Plus Vascular Injury Panel 2 Human Kit is used to simultaneously measure biomarkers related to vascular injury and endothelial dysfunction This electrochemiluminescent multiplex assay allows researchers to quantify biomarkers such as VCAM-1 ICAM-1 E-Selectin P-Selectin and Thrombomodulin from human serum plasma and cell culture supernatants The kit includes a 96-well plate coated with capture antibodies detection antibodies Read Buffer Calibrator Diluent and lyophilized SULFO-TAG conjugated detection antibodies This sensitive and reproducible kit enables vascular biology research
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The protein encoded by this gene removes 5 overhanging flaps in DNA repair and processes the 5 ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5 end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.
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The Meso Scale Discovery V-PLEX Plus Metabolic Panel 1 Human Kit is a multiplex immunoassay measuring insulin leptin resistin PAI-1 active and MCP-1 in human serum plasma and cell culture supernatants It includes a 96-well plate with capture antibodies detection antibodies calibrators controls diluent read buffer wash buffer and plate seals With a sensitivity of 0 3-2 pg/mL it requires 25 L of sample Results are available in 3 5 hours using an MSD instrument with electrochemiluminescence detection enabling efficient analysis of metabolic and inflammatory biomarkers related to obesity and diabetes
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The Meso Scale Discovery Muscle Injury Panel 2 Rat Kit is designed to measure biomarkers associated with muscle injury and inflammation in rat serum plasma and tissue culture media The multiplex immunoassay kit contains a 96-well plate coated with capture antibodies for Creatine Kinase MM Fatty Acid Binding Protein 3 and Myoglobin The kit includes detection antibodies calibrators controls 10X Diluent Read Buffer and Plate Seals This product allows for the simultaneous quantitative measurement of multiple muscle injury biomarkers from a single sample The electrochemiluminescent detection method provides high sensitivity wide dynamic range and low sample consumption
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More